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Donor Registry Transplant Data

Data about transplants using unrelated marrow donors and umbilical cord blood units from the donor registry of the C.W. Bill Young Cell Transplantation Program (Program), including the National Cord Blood Inventory, are reported annually.

These data include the number of transplants performed along with the following information:

• Diagnoses for which transplants have been performed most often, including blood cancers such as leukemia and lymphoma as well as myelodysplastic syndromes.
• Cell sources used for transplants: bone marrow, peripheral blood stem cells (PBSC), and umbilical cord blood.
• The age, race, and ethnic heritage of patients who received transplants.

On this page:

• Figure 1. Growth in Number of Registry Transplants
• Figure 2. Registry Transplants by Patient Diagnosis
• Figure 3. Registry Transplants by Patient Age
• Figure 4. Registry Transplants by Patient Race
• Figure 5. Registry Transplants by Patient Ethnicity
• Figure 6. Registry Transplants by Cell Source
• Figure 7. Role of Cord Blood in Registry Transplants by Patient Race
• Figure 8. Role of Cord Blood in Registry Transplants by Patient Ethnicity

Figure 1. Growth in Number of Registry Transplants 

View larger image, Detailed Description [D]

The number of transplants performed through the registry has more than doubled compared with 7 years ago: from 2,600 transplants in 2005 to more than 5,800 in 2012.

Figure 2. Registry Transplants by Patient Diagnosis 

 
View larger image, Detailed Description [D]

The blood cancers (hematologic malignancies) for which patients received an unrelated bone marrow or cord blood unit transplant most often during 2011 were:

• Acute Myelogenous Leukemia (AML): 35%
• Acute Lymphoblastic Leukemia (ALL): 16%
• MyelodysplasticSyndromes (MDS): 14%
• Non-Hodgkin Lymphoma (NHL): 11%
• Other Leukemias, including Juvenile Leukemias and Chronic Lymphocytic Leukemia (OL): 5%
• Chronic Myelogenous Leukemia (CML): 4%
• Hodgkin Lymphoma (HL): 2%

Since 2005, the number of transplants has increased for patients who were diagnosed with AML, ALL, MDS, HNL, OL, and HL. For patients diagnosed with CML, the number has increased steadily since 2007.

Figure 3. Registry Transplants by Patient Age 

View larger image, Detailed Description [D]

The number of transplants performed for all age groups continues to increase.

In 2012, children (0 to 17 years) received 20 percent of transplants, adults 18 to 50 years received 36 percent of transplants, adults 51 to 64 years received 31 percent of transplants, and adults over age 65 received 13 percent of transplants.

Figure 4. Registry Transplants by Patient Race* 

For the last several years, transplants have increased steadily for patients of most races.

Figure 5. Registry Transplants by Patient Ethnicity* 

View larger image, Detailed Description [D]

Each year since 2005, the number of transplants has increased for patients who reported their ethnicity as Hispanic or Latino.

Figure 6. Registry Transplants by Cell Source 

View larger image, Detailed Description [D]

During 2012, cord blood units were used in 1,191 transplants. The National Cord Blood Inventory provided 714 cord blood units for these transplants.

Also, 1,150 transplants were performed using bone marrow and more than 3,400 transplants used peripheral blood stem cells.

Figure 7. Role of Cord Blood in Registry Transplants by Patient Race* 

View larger image, Detailed Description [D]

In 2012, cord blood was used to help 20 percent of patients from all races who received a transplant.

Figure 8. Role of Cord Blood in Registry Transplants by Patient Ethnicity* 

View larger image, Detailed Description [D]

Over one third of patients who recorded their ethnicity as Hispanic or Latino received a cord blood transplant.

*Patients are asked to record both their race and ethnicity. Patients who indicated their ethnicity as Hispanic or Latino are also included in the race data.