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Donor Registry Transplant Data

Data about transplants using unrelated marrow donors and umbilical cord blood units from the donor registry of the C.W. Bill Young Cell Transplantation Program (Program), including the National Cord Blood Inventory, are reported annually.

These data include the number of transplants performed along with the following information:

  • Diagnoses for which transplants have been performed most often, including blood cancers such as leukemia and lymphoma as well as myelodysplastic syndromes.
  • Cell sources used for transplants: bone marrow, peripheral blood stem cells (PBSC), and umbilical cord blood.
  • The age, race, and ethnic heritage of patients who received transplants.

On this page:

Figure 1. Growth in Number of Registry Transplants 

Figure 1. Growth in Number of Registry Transplants.

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Since the registry was established in 1987, it has facilitated nearly 68,000 marrow and cord blood transplants for patients who do not have a matching donor in their family. In 2016, the registry facilitated nearly 6,200 transplants.

Figure 2. Registry Transplants by Patient Diagnosis 


 
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The blood cancers (hematologic malignancies) for which patients received an unrelated bone marrow or cord blood unit transplant most often during 20164 were:

  • Acute Myelogenous Leukemia (AML): 36%
  • Acute Lymphoblastic Leukemia (ALL): 15%
  • MyelodysplasticSyndromes (MDS): 20%
  • Non-Hodgkin Lymphoma (NHL): 8%
  • Other Leukemias, including Juvenile Leukemias and Chronic Lymphocytic Leukemia (OL): 3%
  • Chronic Myelogenous Leukemia (CML): 3%
  • Hodgkin Lymphoma (HL): 1%

The number of transplants continues to increase, with the largest areas of growth in AML, ALL and MDS.

Figure 3. Registry Transplants by Patient Age 

View larger image, Detailed Description [D]

In 2016, children (0 to 18 years) received 19% of transplants, adults 19 to 50 years received 31% of transplants, adults 51 to 64 years received 31% of transplants, and adults age 65 and over received 18% of transplants.

(Numbers may not add up to 100 percent due to rounding.)

Figure 4. Registry Transplants by Patient Race* 

Figure 4a.
American Indian or
Alaska Native Race

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Detailed Description [D]

Figure 4b.
Asian Race



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Detailed Description [D]

Figure 4c.
Black or African American Race

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Detailed Description [D]

Figure 4d.
White Race

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Detailed Description [D]

Figure 4e.
Native Hawaiian or
Pacific Islander Race

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Detailed Description [D]

 

For the last several years, transplants have increased steadily for patients of most races.

Figure 5. Registry Transplants by Patient Ethnicity* 

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Since 2005, transplants for patients who reported their ethnicity as Hispanic or Latino has remained steady, often increasing.

Figure 6. Registry Transplants by Cell Source 

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During 2016, cord blood units were used in 852 transplants. The National Cord Blood Inventory provided 531 cord blood units for these transplants.

Also, 1,240 transplants were performed using bone marrow and 4,074 transplants used peripheral blood stem cells.

Figure 7. Role of Cord Blood in Registry Transplants by Patient Race* 

View larger image, Detailed Description [D]

In 2016, cord blood was used to help 29% of patients from all races who received a transplant.

Donor Registry Data

The Program’s donor registry, also called the Be The Match Registry®, is operated under Federal contracts by the National Marrow Donor Program® (NMDP). Donor registry data are reported from Oct. 1 - Sept. 30 by the NMDP.

Patient Outcomes

Find more information about patient survival using marrow donors or donated cord blood units from the registry.

Successful Outcomes Depend on a Matching Donor