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U.S. Department of Health and Human Services
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National Marrow Donor Program, a CWBYCTP Contractor

In 2017, the Health Resources and Services Administration (HRSA) awarded three contracts to support the functions of the various components of the C.W. Bill Young Cell Transplantation Program (CWBYCTP). The National Marrow Donor Program® (NMDP®), also known as Be The Match®, was awarded two of the contracts for the CWBYCTP:

NMDP has operated under Federal contract since 1987 through the National Bone Marrow Donor Registry (NBMDR), and since September 2006 through the CWBYCTP.

NMDP/Be The Match is a nonprofit organization that helps people who need a potentially life-saving bone marrow or umbilical cord blood transplant. NMDP/Be The Match helps by connecting patients, doctors, donors, and researchers to the resources they need to help more people live longer, healthier lives.

CWBYCTP Components Work Together

A transplant from an unrelated marrow donor or cord blood unit involves many steps. Each step of the transplant process is in some way connected to the OPA or SPA-CC. To make the steps connect smoothly, NMDP/Be The Match has:

  • A network of national and international organizations, including transplant centers, cord blood banks, donor centers, recruitment centers, apheresis centers, and collection centers. These facilities follow procedures, standards, and policies created by the NMDP/Be The Match.
  • An electronic search process (Single Point of Access) through the NMDP/Be The Match’s software applications that provides information on potential marrow donors and donated cord blood units throughout the world.
  • Procedures and policies to ensure that the safety, confidentiality, and rights of donors and patients are protected.
  • Staff and services to support patients and their families from diagnosis through survivorship and donors throughout the registration and donation process.
  • Outcomes data about donors and patients that are made available to researchers and the public.

Emergency Response Plans

The NMDP/Be The Match has developed and tested plans for keeping the organization working through emergencies, as required by the contract.

Standards and Criteria of NMDP/Be The Match Centers

Each year, NMDP/Be The Match certifies to the Health Resources and Services Administration (HRSA) that NMDP/Be The Match Standards https://bloodcell.transplant.hrsa.gov/images/exitsmall.png are in place and being followed at each NMDP/Be The Match center. As specified by the CWBYCTP requirements, NMDP/Be The Match provides these standards to the public. Any significant change to a standard will be posted for public comment before the change is put into effect.

Donor and patient safety are primary concerns of NMDP/Be The Match. NMDP/Be the Match standards are designed to ensure that donors and patients receive high quality care and that government standards are met. These standards include donor recruitment, collection, and transportation procedures and requirements. The facility standards define specific characteristics of an NMDP/Be The Match center, the qualifications for its medical director and staff, and the support services, policies and procedures that are required. Each center is monitored for ongoing compliance. A center that does not comply with the standards may be removed from the NMDP/Be The Match network.

The network is made up of these types of organizations:

  • Apheresis centers collect blood-forming cells from a donor's bloodstream (sometimes called peripheral blood stem cells or PBSC). A donor center representative will arrange the collection of PBSC at an apheresis center, which is usually located in a hospital or blood bank.
  • Collection centers collect bone marrow from donors. Collection centers are located in hospitals. A donor center representative will arrange the collection of bone marrow at a collection center, which is located in a hospital.
  • Cord blood banks collect, process, test, and store donated umbilical cord blood.
  • Donor centers help marrow donors throughout the donation process.
  • Recruitment centers recruit potential marrow donors, tell communities about the need for more donors, and raise funds to add more donors to the registry.
  • Transplant centers treat patients who need a bone marrow or umbilical cord blood transplant. Transplant centers conduct searches to find marrow donors and cord blood units that closely match their patients, prepare the patient for transplant, infuse the healthy blood-forming cells, and provide care after transplant. Patients receive high quality treatment that meets the current standard of care for transplantation.
Network Centers
Safety and Confidentiality for Donors and Patients

All organizations in the CWBYCTP protect patient and donors by following these standards: