In 1987, the National Bone Marrow Donor Registry (NBMDR) was initiated through a congressionally-directed grant from the U.S. Department of the Navy and formally established in 1990 as a responsibility of the U.S. Department of Health and Human Services (HHS), with oversight initially by the National Institutes of Health (National Heart, Lung, and Blood Institute) and, since 1994, by the HHS Health Resources and Services Administration (HRSA).
In December 2005, Congress passed the Stem Cell Therapeutic and Research Act (Stem Cell Act 2005), Public Law 109-129. The Stem Cell Act 2005 amended the Public Health Service Act and required the HHS Secretary, through HRSA, to rewrite the provisions that established and maintained the NBMDR. The provisions were rewritten to establish and maintain the C.W. Bill Young Cell Transplantation Program (CWBYCTP), the successor to the NBMDR. The Stem Cell Therapeutic and Research Reauthorization Act of 2010 (Stem Cell Act 2010), Public Law 111-264, was signed in December 2010 and the Stem Cell Therapeutic and Research Reauthorization Act of 2015 (Stem Cell Act 2015), Public Law 114-104, was signed in 2015.
The Stem Cell Acts of 2005, 2010, and 2015 authorize the following:
Advisory Council on Blood Stem Cell Transplantation (ACBSCT). The law also requires the ACBSCT to make recommendations on issues about the CWBYCTP to the Secretary of the HHS.
The Stem Cell Therapeutic and Research Reauthorization Act requires the Secretary of HHS, through HRSA, to submit to Congress an annual report on the activities of the CWBYCTP, NCBI, and ACBSCT.