Glossary for the U.S. Transplant Data by Center Report
A measure of how the disease responded to treatment before the patient received a bone marrow, peripheral blood or umbilical cord blood transplant. The disease status can help predict the likelihood of a better or worse survival outcome after transplantation.
In these reports, disease status is included only for leukemias, lymphomas, myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN) and multiple myeloma. Disease status are categorized as:
- In remission—The disease responded well to treatment. There is no clinical evidence of disease.
- Not in remission—The disease is not responding to treatment. There is still evidence of disease.
- No data—The disease status was not available.
Biological relationship between the patient and the donor who provided the blood-forming cells.
- Autologous—The patient's own cells were collected, stored and infused back into the patient.
- Allogeneic—Another person donated bone marrow, peripheral blood, or an umbilical cord blood unit. These cells match the patient’s human leukocyte antigen (HLA) type. Specific allogeneic types include:
- HLA-identical sibling—The brother or sister who donated cells is the patient's biological sibling who matches the patient’s HLA type.
- HLA-identical twin – The brother or sister who donated cells is the patient’s monozygotic twin who shares the patient’s DNA.
- Other related donor—The family member who donated cells is related biologically to the patient and is not included in the HLA-matched sibling or identical twin category. The donor might have variable degrees of mismatch to the patient.
- Unrelated—The person who donated cells is not biologically related to the patient.
Human Leukocyte Antigen (HLA)
Proteins on cells that make each person's tissue type, which varies from person to person.
HLA typing is used to match patients and donors for a bone marrow, peripheral blood or umbilical cord blood transplant. A person's HLA type is identified by testing a blood sample or swab of cheek cells.